N-acetylcysteine for the treatment of clove oil-induced fulminant hepatic failure.

نویسندگان

  • Jeffrey S Eisen
  • Gideon Koren
  • David N Juurlink
  • Vicky L Ng
چکیده

We present a 3-month-old female who developed fulminant hepatic failure after ingesting less than 8 mL of clove oil. Initial treatment involved gastrointestinal decontamination, supportive measures, and admission to hospital. She subsequently developed fulminant hepatic failure and was treated with intravenous N-acetylcysteine (N-AC) according to a protocol used for acetaminophen poisoning. Over the next 72 h her liver synthetic function and clinical status improved, and she made a complete recovery. Previous reported cases of clove oil toxicity and the potential role of N-AC therapy are reviewed.

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عنوان ژورنال:
  • Journal of toxicology. Clinical toxicology

دوره 42 1  شماره 

صفحات  -

تاریخ انتشار 2004